WebMar 3, 2024 · thunberginol A (2). The cytotoxic activity of the compounds 1 and 2 from H. macrophylla was performed by the colorimet-ric method against MCF-7 breast cancer lines. The IC 50 values of compounds 1 and 2 on MCF-7 breast cancer lines were 631.04 μg/ml and 180.33 μg/ml, respectively. Compound showed stronger cytotoxicity than compound 2. WebThunberginol A Substances of Biological Interest active profile. Top Gene Interactions. Related Pathways. Load more Thunberginol A Interacts with Diseases. Disease: Inference …
A new total synthesis of natural isocoumarin, thunberginol B
WebJul 20, 2007 · Thunberginol B, a natural isocoumarin derivative, was isolated from Hydrangeae Dulcis Folium, the fermented leaves of Hydrangea macrophylla SERINGE var. thunbergii MAKINO, as antiallergic constituents.16-19 Thunberginol B (10) inhibited the histamine release from rat peritoneal mast cells induced by compound 48/80, calcium … WebSep 3, 2015 · EMNCM (SS/DV) Zachary T. Montello, USN. Command Master Chief, Nuclear Power Training Unit, Charleston S.C. VIEW BIO. This is an official U.S. Navy Web site. … feeding during ttm
Inhibitory effects of thunberginols A and B isolated from …
WebJun 8, 2024 · Decne. 3S-thunberginol C 6-O-β-D-glucopyranoside was determined as a mixture of boat-like conformers based on NMR evidence and density functional theory (DFT) calculations. The in vitro inhibition of soluble epoxide hydrolase (sEH) by the isolated compounds was comparable to that of AUDA (positive control), yielding IC 50 values … Webthunberginol C. Sources of phenyldihydroisocoumarins: To get an overview about the naturally occurring diversity of phenyldihydroisocoumarins, a literature database search was carried out on January 29, 2024 using the Reaxys and Scifinder databases with 3-phenyldihydroisocoumarin (figure 1) as the starting substance. WebThunberginols C, D, and E, new antiallergic and antimicrobial dihydroisocoumarins, and thunberginol G 3'-O-glucoside and (-)-hydrangenol 4'-O-glucoside, new dihydroisocoumarin glycosides, from Hydrangeae Dulcis Folium. [Pubmed: 1363465] Chem Pharm Bull (Tokyo). 1992 Dec;40 (12):3352-4. feeding ducks peanuts